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Neuroendocrine tumors are divided into 2 groups: orthoendocrine (producing hormones corresponding to the organ in which they develop) and paraendocrine (producing biologically active substances uncharacteristic of their localization). Most often in oncological practice, pancreatic apudoma is diagnosed. In the endocrine islet cell structures of this digestive organ, biologically active substances such as insulin, pancreastatin, polypeptides, somatostatin, glucagon are produced, so patients with pancreatic apudoma experience pronounced negative signs of their excess in the body.

In addition to pancreatic neuroendocrine neoplasms, a person can develop: Abnormal structures of the central and peripheral nervous system (pituitary gland, adrenal medulla, hypothalamus, and so on). Apudoma of the thyroid gland. Tumor of neuroectodermal C-cells, which are part of Tenormin glands. Neuroendocrine tumor structures of the gastrointestinal tract.

Symptoms and treatment of apudoma in the pancreas, thyroid gland and gastrointestinal tract. Significantly less often, the formation of NETs occurs in the mucous membranes of the urinary and respiratory tract, as well as in the skin. The development of apudoma of any organ is directly related to the appearance of hormonal imbalance in the human blood.
It has been scientifically proven that a large percentage of abnormal cells have specific receptors, which, with active hormonal stimulation, begin uncontrolled division, forming large quantities of similar mutated cell structures with a certain degree of malignancy.







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Any neuroendocrine tumor of the pancreas can be classified according to the level of malignancy to one of three morphological and histological groups: Borderline, which are currently benign, but capable of starting the process of malignancy under the influence of certain negative factors.
These include rare types of NET, insulinoma, vipoma, gastrinoma, with a degree of malignancy not exceeding 10% and not prone to germination in the surrounding tissue structures and vessel walls. Apudoma of the gastrointestinal tract, which has a low, from 10 to 50%, degree of malignancy.